REACTIVATING THE EXTRACELLULAR MATRIX SYNTHESIS OF SULFATED GLYCOSAMINOGLYCANS AND PROTEOGLYCANS TO IMPROVE THE HUMAN SKIN ASPECT AND ITS MECHANICAL PROPERTIES

Reactivating the extracellular matrix synthesis of sulfated glycosaminoglycans and proteoglycans to improve the human skin aspect and its mechanical properties

Hanane Chajra,1 Daniel Auriol,1 Francine Joly,2 Aurélie Pagnon,3 Magda Rodrigues,4 Sophie Allart,4 Gérard Redziniak,5 Fabrice Lefevre1 1Libragen, Induchem (Givaudan Active Beauty), Toulouse, 2Sephra Pharma, Puteaux, 3Novotec, Bron, 4Centre de Physiopathologie de Toulouse-Purpan, Toulouse, 5Cosmetic Inventions, Antony, France Backgroun

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Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold

The chemistry of 1,3,4-thiadiazole is schulterblattanastomose one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities.Several modifications in the thiadiazole ring have been made, proving it to be more potent and highly effective with a less toxic scaffold for various shure ua874 bi

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